Primaquine Detailed Information

The active ingredient in Primaquine is **Primaquine phosphate**. Inactive ingredients may include lactose, magnesium stearate, and microcrystalline cellulose.

Common side effects of Primaquine include:

• Headache
• Abdominal pain
• Nausea or vomiting
• Dizziness
• Fatigue

Less common but serious side effects include:

• Severe allergic reactions (rash, swelling, difficulty breathing)
• Hemolytic anemia (especially in patients with G6PD deficiency)
• Liver problems (yellowing of the skin or eyes, dark urine)
• Severe gastrointestinal distress

If you experience severe side effects, seek medical attention immediately.

Primaquine is typically taken as a **daily oral dose**, with or without food. The dosage depends on the type of infection being treated. For malaria, it is often prescribed as a 14-day regimen, while for prevention, it may be taken over a shorter course.

Primaquine may interact with other medications, including:

• Medications for malaria (e.g., Chloroquine, Quinine): May require dose adjustments.
• Antacids: Can decrease Primaquine's absorption.
• Other medications affecting red blood cells (e.g., certain antibiotics, antimalarials): Can increase the risk of hemolytic anemia.
• Drugs affecting liver function: May alter Primaquine metabolism.

Always inform your healthcare provider about all medications you are taking.

Primaquine begins to work within **several hours** to a day, but full symptom relief for malaria may take **several days to weeks** depending on the severity of the infection. It is essential to complete the full course of treatment to prevent relapse.

If you experience severe side effects, such as suicidal thoughts, heart irregularities, or seizures, stop taking

If you experience severe side effects such as signs of hemolytic anemia (fatigue, pale skin, jaundice), severe allergic reactions, or liver problems, stop taking Primaquine and seek immediate medical attention.